Nouvelles observations sur les axolotls, batraciens urodeles de Mexico (Siredon mexicanus vel Humboldtii) nes dans la menagerie des reptiles au Mus_eum d'Histoire naturelle, et qui y subissent des metamorphose. Reproduction, dans la menagerie des reptiles au Museum d'Histoire naturelle, des axolotls, batraciens, urodeles a branchies persistantes de Mexico (Siredon mexicanus, vel Humboldtii), qui n'avient encore jamais ete vus vivante en Europe. Recueil d'observations de zoologie et d'anatomie comparee. Voyage aux regions equinoxiales du nouveau continent. Recherches anatomique sur les reptiles regardes encore comme douteux par les naturalistes faites a l'occasion de l'axolotl, rapport_e par M. The history of the oldest self-sustaining laboratory animal: 150 years of axolotl research. With the recent completion of the axolotl genome assembly and established methods to manipulate gene functions, the axolotl is poised to provide new insights about paedomorphosis and the role of thyroid hormone in development and evolution.Īmbystoma axolotl metamorphosis paedomorphosis thyroid hormone. In this perspective, we first introduce the axolotl and the various meanings of paedomorphosis, and then stress the need to move beyond endocrinology-guided approaches to understand the axolotl's hypothyroid state. The evolution of paedomorphosis allowed axolotls to exploit relatively permanent habitats in Mexico, and preadapted axolotls for domestication and laboratory study. Instead, the axolotl exhibits a paedomorphic mode of development that enables a completely aquatic life cycle.
Unlike close tiger salamander relatives that undergo a thyroid hormone regulated metamorphosis, the axolotl does not typically undergo a metamorphosis. However, not forgotten is the axolotl's equally amazing ability to thwart aspects of tissue maturation and retain juvenile morphology into the adult phase of life. Much current attention is focused on the axolotl's amazing ability to regenerate tissues and whole organs after injury. The Mexican axolotl ( Ambystoma mexicanum) is an important model organism in biomedical research.
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